Publications

2024

  • "Catalysis driven by an amyloid-substrate complex"

    Taka Sawazaki, Daisuke Sasaki, Youhei Sohma
    Proc. Natl. Acad. Sci. U.S.A., 2024, 121, e2314704121. DOI:10.1073/pnas.2314704121

  • "Redesign of a thioflavin-T-binding protein with a flat β-sheet to evaluate a thioflavin T-derived photocatalyst with enhanced affinity"

    Yuina Miura, Sae Namioka, Atsushi Iwai, Norio Yoshida, Hiroyuki Konno, Youhei Sohma, Motomu Kanai, Koki Makabe
    Int. J. Biol. Macromol. 2024, 269, 131992. DOI:10.1016/j.ijbiomac.2024.131992

  • "Leuco Ethyl Violet as Self‐Activating Prodrug Photocatalyst for In Vivo Amyloid‐Selective Oxygenation"

    Masahiro Furuta, Suguru Arii, Hiroki Umeda, Ryota Matsukawa, Katsuyuki Shizu, Hironori Kaji, Shigehiro A. Kawashima, Yukiko Hori, Taisuke Tomita, Youhei Sohma, Harunobu Mitsunuma, and Motomu Kanai
    Adv. Sci., 2024, 2401346. DOI:10.1002/advs.202401346

  • "Modular synthetic strategy for N/C-terminal protected amyloidogenic peptides"

    Taka Sawazaki, Youhei Sohma
    J. Peptide Sci. (Special issue: PeptideTalents), 2024, 30, e3546. DOI:10.1002/psc.3546

2023

  • "Photo-oxygenation of histidine residue inhibits α-synuclein aggregation"

    Reito Nakamura, Ikumi Tomizawa, Atsushi Iwai, Tetsuo Ikeda, Kota Hirayama, Yung Wen Chiu, Takanobu Suzuki, Airi Tarutani, Tatsuo Mano, Atsushi Iwata, Tatsushi Toda, Youhei Sohma, Motomu Kanai, Yukiko Hori, Taisuke Tomita
    FASEB Journal, 2023, 37, e23311. DOI:10.1096/fj.202301533R

  • "Rose bengal promoted catalytic amyloid-β oxygenation via sono-activation"

    Wataru Atsumi, Keiichi Kawabata, Mina Yamane, Miku Oi, Harunobu Mitsunuma, Youhei Sohma, Yukiko Hori, Taisuke Tomita, Motomu Kanai
    Synlett (Special Issue dedicated to Keith Fagnou), 2023. DOI:10.1055/a-2182-7614

  • "Quantitative assays for catalytic photo-oxygenation of Alzheimer disease-related tau proteins"

    Hiroki Umeda, Taka Sawazaki, Masahiro Furuta, Takanobu Suzuki, Shigehiro A. Kawashima, Harunobu Mitsunuma, Yukiko Hori, Taisuke Tomita, Youhei Sohma, Motomu Kanai
    ACS Chemical Neuroscience, 2023, 14, 2710-2716. DOI:10.1021/acschemneuro.3c00264

  • Contributing to Society Newsletter"これまでの研究活動を一旦振り返って"

    相馬洋平
    日本ペプチド学会　ニュースレター　No. 128（2023年4月） https://www.peptide-soc.jp/files/newsletter/PNJ128.pdf

  • "Attenuation of α-synuclein aggregation by catalytic photo-oxygenation"

    Atsushi Iwai, Reito Nakamura, Ikumi Tomizawa, Harunobu Mitsunuma, Yukiko Hori, Taisuke Tomita, Youhei Sohma, Motomu Kanai
    Chem. Commun., 2023, 59, 5745-5748. DOI:10.1039/D3CC00665D

2022

  • Article Commentary"Promotion in the Clearance of Aggregated Aβ in vivo using Amyloid Selective Photo-Oxygenation Technology”

    Yukiko Hori, Youhei Sohma, Motomu Kanai, Taisuke Tomita
    Neuroscience Insights, 2022, 17. DOI:10.1177/26331055221126179

  • "Activatable Iodinated BODIPYs for Selective Imaging and Photodynamic Disruption of Amyloid Structures in Pathogenic Bacterial Biofilms"

    Joaquim Torra,Taka Sawazaki, Patricia Bondia, Santi Nonell, Motomu Kanai, Youhei Sohma, Cristina Flors
    Sens. Actuators B Chem., 2022, 132475. DOI:10.1016/j.snb.2022.132475

  • "Single crystal spectroscopy and multiple structur